Anti-SENP1 Antibody
419.70 $ – 243.98 $
Western Blot
analysis of HeLa whole cell lysate, HL60 whole cell lysate, Jurkat whole cell lysate, Mouse heart tissue, Mouse brain tissue, Mouse spleen tissue, Mouse stomach tissue, Mouse skeletal muscle tissue
All lanes: SENP1 antibody at 2.7µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-50469
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Protease that catalyzes two essential functions in the SUMO pathway (PMID:10652325, PMID:15199155, PMID:16253240, PMID:16553580, PMID:21829689, PMID:21965678, PMID:23160374, PMID:24943844, PMID:25406032, PMID:29506078). The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2 (PMID:16253240). Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity (PMID:21829689). Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity (PMID:23160374). Deconjugates SUMO2 from MTA1 (PMID:21965678). Deconjugates SUMO1 from METTL3 (PMID:29506078). Desumoylates CCAR2 which decreases its interaction with SIRT1 (PMID:25406032). Deconjugates SUMO1 from GPS2 (PMID:24943844). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB, IHC, IF |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Sentrin-specific protease 1 protein (63-214AA) |
| Specificity | SENP1 antibody detects endogenous level of SENP1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
Related Products
-
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page