Anti-SH3GLB1 Antibody
390.54 $ – 243.25 $
Western blot
All lanes: Endophilin-B1 antibody at 2µg/mL + Mouse kidney tissue
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Catalog No
IGX-48780
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | May be required for normal outer mitochondrial membrane dynamics (PMID:15452144). Required for coatomer-mediated retrograde transport in certain cells . May recruit other proteins to membranes with high curvature. May promote membrane fusion (PMID:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PMID:16227588). Isoform 1 acts proapoptotic in fibroblasts . Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PMID:17891140). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PMID:21068542). Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PMID:20643123). Isoform 2 acts antiapoptotic in neuronal cells; involved in maintenance of mitochondrial morphology and promotes neuronal viability . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:500-1:2000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Endophilin-B1 protein (1-365AA) |
| Specificity | SH3GLB1 antibody detects endogenous level of SH3GLB1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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