Anti-SLC25A33 Antibody
418.43 $ – 243.25 $
Immunohistochemistry of paraffin-embedded human testis tissue with rabbit anti-SLC25A33 antibody IGX-44018 at dilution 1:100.
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Catalog No
IGX-44018
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PMID:25320081). Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism (PMID:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PMID:25320081). Is inhibited strongly by pyridoxal 5′-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PMID:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PMID:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production (PMID:20453889, PMID:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation (PMID:14715278). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC, IF |
| Recommended Dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Solute carrier family 25 member 33 protein (66-120AA) |
| Specificity | SLC25A33 antibody detects endogenous level of SLC25A33 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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