Anti-STIM1 Antibody
419.18 $ – 243.68 $
Immunohistochemistry of paraffin-embedded human lymph node tissue with rabbit anti-STIM1 antibody IGX-43164
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Catalog No
IGX-43164
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores (PMID:15866891, PMID:16005298, PMID:16208375, PMID:16537481, PMID:16733527, PMID:16766533, PMID:16807233, PMID:18854159, PMID:19249086, PMID:22464749, PMID:24069340, PMID:24351972, PMID:24591628, PMID:26322679, PMID:25326555, PMID:28219928). Acts as Ca2+ sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca2+ depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit ORAI1 (PMID:16208375, PMID:16537481). Involved in enamel formation (PMID:24621671). Activated following interaction with STIMATE, leading to promote STIM1 conformational switch (PMID:26322679). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Stromal interaction molecule 1 protein (2-350AA) |
| Specificity | STIM1 antibody detects endogenous level of STIM1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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