Anti-TDP1 Antibody
391.72 $ – 243.98 $
Western blot
All lanes: Tyrosyl-DNA phosphodiesterase 1 antibody at 8µg/mL
Lane 1: MCF-7 whole cell lysate
Lane 2: Mouse lung tissue
Lane 3: Rat brain tissue
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-47976
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3′-phosphodiester bond, giving rise to DNA with a free 3′ phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3′-phosphoglycolates on protruding 3′ ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3’exonuclease activity and can remove a single nucleoside from the 3’end of DNA and RNA molecules with 3’hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3’phosphate. |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB, IHC, IP |
| Recommended Dilutions | WB: 1:200-1:2000, IHC: 1:20-1:200, IP: 1:200-1:2000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Tyrosyl-DNA phosphodiesterase 1 protein (1-260AA) |
| Specificity | TDP1 antibody detects endogenous level of TDP1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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