Anti-TRMT112 Antibody
419.18 $ – 243.68 $
Immunohistochemistry of paraffin-embedded human lung cancer with rabbit anti-TRMT112 antibody IGX-41821
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Catalog No
IGX-41821
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Acts as an activator of both rRNA/tRNA and protein methyltransferases (PMID:25851604, PMID:18539146, PMID:20308323, PMID:25851604, PMID:31328227). Together with methyltransferase BUD23, methylates the N7 position of a guanine in 18S rRNA (PMID:25851604). The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on ‘Gln-185’, using S-adenosyl L-methionine as methyl donor (PMID:18539146). The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (PMID:20308323). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production (PMID:25851604). Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA (PMID:31328227). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human tRNA methyltransferase 112 homolog protein (1-125AA) |
| Specificity | TRMT112 antibody detects endogenous level of TRMT112 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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