Anti-USP30 Antibody
419.18 $ – 243.68 $
Western blot
All lanes: USP30 antibody at 7µg/mL + Mouse liver tissue
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-48528
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin’s ability to drive mitophagy (PMID:18287522, PMID:24896179, PMID:25527291, PMID:25621951). Preferentially cleaves ‘Lys-6’- and ‘Lys-11’-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signaling (PMID:25621951). Does not cleave efficiently polyubiquitin phosphorylated at ‘Ser-65’ (PMID:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:500-1:2000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Ubiquitin carboxyl-terminal hydrolase 30 protein (101-400AA) |
| Specificity | USP30 antibody detects endogenous level of USP30 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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