Anti-WDR5 Antibody
390.58 $ – 243.28 $
Western blot
All lanes: WDR5 antibody at 2µg/mL + A431 whole cell lysate
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-47754
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Contributes to histone modification (PMID:19131338, PMID:19556245, PMID:19103755, PMID:20018852, PMID:16600877, PMID:16829960). May position the N-terminus of histone H3 for efficient trimethylation at ‘Lys-4’ (PMID:16829960). As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ‘Lys-4’ of histone H3 (PMID:19556245). H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation (PMID:18840606). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PMID:19103755, PMID:20018852). May regulate osteoblasts differentiation . In association with RBBP5 and ASH2L, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (PMID:21220120, PMID:22266653). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:200-1:1000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human WD repeat-containing protein 5 protein (1-334AA) |
| Specificity | WDR5 antibody detects endogenous level of WDR5 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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