Anti-WNT7A Antibody
417.46 $ – 242.68 $
Immunofluorescence staining of HepG2 cells with rabbit anti-WNT7A antibody IGX-44360 at dilution 1:100.
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Catalog No
IGX-44360
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway . Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PMID:16826533). Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (PMID:30026314). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes . Required for normal neural stem cell proliferation in the hippocampus dentate gyrus . Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation . Promotes formation of synapses via its interaction with FZD5 . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC, IF |
| Recommended Dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Protein Wnt-7a protein (126-302AA) |
| Specificity | WNT7A antibody detects endogenous level of WNT7A protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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