Anti-WT1 Antibody
418.43 $ – 243.25 $
Immunohistochemistry of paraffin-embedded human endometrial cancer with rabbit anti-WT1 antibody IGX-41275
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Catalog No
IGX-41275
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Transcription factor that plays an important role in cellular development and cell survival (PMID:7862533). Recognizes and binds to the DNA sequence 5′-GCG(T/G)GGGCG-3′ (PMID:7862533, PMID:17716689, PMID:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PMID:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PMID:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PMID:19123921). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Wilms tumor protein (1-449AA) |
| Specificity | WT1 antibody detects endogenous level of WT1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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