Anti-ZFP57 Antibody
417.46 $ – 242.68 $
Western Blot
analysis of HepG2 whole cell lysate, 293 whole cell lysate, Mouse brain tissue
All lanes: ZFP57 antibody at 13.6µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-49505
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs) (PMID:18622393, PMID:30602440). Acts together with ZNF445, but ZNF445 seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance (PMID:30602440). Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. Binds to a 5′-TGCCGC-3′ consensus sequence and recognizes the methylated CpG within this element . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Recommended Dilutions | WB: 1:500-1:5000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Zinc finger protein 57 homolog protein (183-295AA) |
| Specificity | ZFP57 antibody detects endogenous level of ZFP57 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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