Cathepsin B
687.14 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-C2097
Supplier
US Biologicals
Size
50 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Cathepsin B is a cysteine protease commonly overexpressed in metastisizing cancer cells. An intracellular (lysosomal) enzyme in peptidase family C1 (papain family), Cathepsin B will hydrolyze proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides. Specific Activity: ≥ 10u/mg enzyme activity Unit Definition: One unit is defined as the amount of enzyme that will hydrolyze 1.0umol Z-RR-pNA per min at 37°C, pH 6.8 in the presence of DTT. Note: One unit defined by Z-RR-pNA equals ~20 units defined with Z-RR-betaNA. Major Bands: 25-27kD, 30-33kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Source Antigen | Human liver |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 27.5 |
Product Properties
| Storage | -70°C |
| Grade | Affinity Purified |
| Purity | ~95% (SDS-PAGE) |
| Form | Supplied as a liquid in 50mM sodium acetate, pH 5.0, 1mM EDTA. |
| Reactivity Life | 12 months |
| Note | For reserch purpose only |
Target Gene
NA
