CD137L, Soluble, Recombinant, Mouse (4-1BBL, TNFSF9)
643.73 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-044652
Supplier
US Biologicals
Size
50 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | The CD137 ligand (CD137L; 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response. Sequence: The extracellular domain of mouse CD137L (aa104-309) is fused at the N-terminus to a FLAG®-tag, expressed in HEK293 cells. Molecular Weight: ~40kD (SDS-PAGE) Endotoxin: <0.01EU/ug (LAL test; Lonza). Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | Recombinant, Mouse, HEK 293 cells |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 40 |
Product Properties
| Storage | 4°C/-20°C |
| Grade | Highly Purified |
| Purity | ≥95% (SDS-PAGE) |
| Form | Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 50ul sterile ddH2O. |
| Reactivity Life | 6 months |
| Note | For reserch purpose only |
Target Gene
NA
