DNA Polymerase Beta, Recombinant, Human (POLB)
698.56 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-171854
Supplier
US Biologicals
Size
100 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | DNA polymerase involved in base excision and repair. Has 5′-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5′ sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3′ end of the arising single-nucleotide gap. Conducts ‘gap-filling’ DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. The protein is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Recombinant protein corresponding to aa2-335 (end) of DNA Polymerase Beta with N-terminal His-tag, expressed in E. coli (Accession# NM_002690). Applications: Suitable for use in DNA synthesis and DNA repair, as an antigen for Western Blot, and for inhibitor screening. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap |
| Source Antigen | Recombinant, E.coli |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 39 |
Product Properties
| Storage | -70°C |
| Grade | Purified |
| Purity | ≥84% (SDS-PAGE) |
| Form | Supplied as a liquid in 40mM Tris-HCl, pH 8.0, 110mM sodium chloride, 2.2mM KCl, 250mM imidazole, 0.04% Tween 20, 20% glycerol. |
| Reactivity Life | 6 months |
| Note | For reserch purpose only |
Target Gene
NA
