DRAK1, Recombinant, Human, GST-Tag (DAP Kinase-related Apoptosis-inducing Protein Kinase 1, Serine/Threonine Kinase 17A, STK17A)
640.66 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-499929
Supplier
US Biologicals
Size
10 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | DRAK1 (STK17A) is a member of the DAP kinase-related apoptosis-inducing protein kinase family. DRAK1 encodes an autophosphorylated nuclear protein with a protein kinase domain which has apoptosis-inducing activity. DRAK1 is capable of autophosphorylation and of phosphorylating myosin light chain as an exogenous substrate. The noncatalytic C-terminal of DRAK1 is crucial for full kinase activity. DRAK1 is highly expressed in placenta, but also in heart, lung, skeletal muscle, kidney, and pancreas. DRAK1 act as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. Source: Recombinant protein corresponding to human DRAK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~83kD Specific Activity: 8.5nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Source Antigen | Recombinant, Insect cells |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 83 |
Product Properties
| Storage | -70°C |
| Grade | Purified |
| Purity | Purified (~70-90%) |
| Form | Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Reactivity Life | 6 months |
| Note | For reserch purpose only |
Target Gene
NA
