Factor VIIa, Recombinant, Human
490.93 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-F0016-14R
Supplier
US Biologicals
Size
10 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Human coagulation factor VII is a single chain protease that circulates in the blood as a weakly active zymogen at concentrations of approximately 10nmol/L. When converted to the active 2 chain form (VIIa), it is a powerful initiator of hemostasis. Recombinant Factor VIIa is a unique hemostatic agent with potential for broad-spectrum applications in bleeding patients with congenital and acquired bleeding abnormalities. At present, recombinant Factor VIIa is only approved for the treatment of hemophilia A and B patients who have acquired antibodies to Factors VIII and IX. Recombinant Human Factor VIIa produced in BHK is a glycosylated polypeptide two-chain dimer consisting of 406 amino acids with a molecular weight of 50kD. Biological Activity: Recombinant Factor-VIIa is fully biologically active when compared to standard. The potency was found to be 50,000 Units/mg. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | BHK cells |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight |
Product Properties
| Storage | -20°C |
| Grade | Highly Purified |
| Purity | ≥98% by SDS-PAEG. Chromatographically purified |
| Form | Supplied as a lyophilized powder. Reconstitute with sterile ddH2O to ≥100ug/ml, which can then be further diluted to other aqueous solutions. |
| Reactivity Life | 6 months |
| Note | For reserch purpose only |
Target Gene
NA
