Goserelin, Human
447.24 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-G8578-90
Supplier
US Biologicals
Size
5 mg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Goserelin has actions similar to those of naturally occurring LHRH. LHRH released from the hypothalamus stimulates receptors on the pituitary gland, which then releases the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Goserelin and other LHRH agonists provide a medical castration that deprives hormonally-dependent tumors of testosterone or estrogen. Normally, LHRH is released in a pulsatile manner to maintain levels of gonadotropins. Goserelin, in contrast, is continuously administered, which leads to downregulation of the LHRH receptor on the pituitary gland and decreased production of FSH and LH. During short-term or intermittent treatment, goserelin has the same stimulatory action as LHRH. This stimulation produces a surge of FSH and LH, which can cause a flare reaction in patients with prostate or breast carcinoma. Sequence: Glu-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-AzGly-NH2 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile buffer ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | Synthetic |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight |
Product Properties
| Storage | -20°C |
| Grade | Highly Purified |
| Purity | ~ 95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified. |
| Form | Supplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O to >100ug/ml, which can then be further diluted to other aqueous solutions. For long term storage, add 0.1%HSA or BSA. |
| Reactivity Life | 12 months |
| Note | For reserch purpose only |
Target Gene
NA
