IL-1 Receptor Type I,Fc, Recombinant, Human (RI, Interleukin-1 Receptor Type I, CD121a, Interleukin-1 Receptor alpha)
576.34 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-044901
Supplier
US Biologicals
Size
50 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2. Biological Activity: Blocks IL-1 beta activity. Sequence: Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4°C Long-term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C. |
| Source Antigen | Recombinant, Human, HEK 293 cells |
| Reactivity | Binds to human IL-1beta. |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 80 |
Product Properties
| Storage | 4°C/-20°C |
| Grade | Highly Purified |
| Purity | >95% (SDS-PAGE) |
| Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2. |
| Reactivity Life | 6 months |
| Note | For reserch purpose only |
Target Gene
NA
