Lactate Dehydrogenase 4, Human
1,132.61 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-L1011-14
Supplier
US Biologicals
Size
100U
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Lactate dehydrogenase (LDH) is present in a wide variety of organisms, including plants and animals. It is an oxidoreductase which catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called Hydroxybutyrate Dehydrogenase (HBD). There are 5 different isoenzymes of LDH, LDH1 to LDH5, each composed of 4 subunits which may be of 2 different types-M and H subunits. These subunits are encoded by two different genes: The M subunit is encoded by gene LDHA whilst the H subunit is encoded by LDHB. Usually LDH2 is the predominant form in the serum. An LDH1 level higher than the LDH2 level suggests myocardial infarction (damage to heart tissues releases heart LDH, which is rich in LDH1, into the bloodstream). Source: Lactate Dehydrogenase Isoenzyme 4 (LDH4) from human liver. Activity: ~30 Units/ml @ 37°C Protein: ~2mg Protein/ml (Commassie) Unit Definition: One unit will catalyze the transformation of one micromole of L-lactate to pyruvate per minute at 37°C and pH 8.55. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | Human liver |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight |
Product Properties
| Storage | 4°C Do Not Freeze |
| Grade | Purified |
| Purity | Purified by Immunoelectrophoresis. Contaminants: ALP: <0.01%; gGT: <0.05%; GOT: <0.1%; GPT: <0.1%. |
| Form | Supplied as a 75% ammonium sulfate suspension in 50mM Tris-chloride, 1mM DTE, 40mM sodium chloride, pH8.3. |
| Reactivity Life | 12 months |
| Note | For reserch purpose only |
Target Gene
NA
