Lactate Dehydrogenase 5, Human
524.58 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-L1011-12M
Supplier
US Biologicals
Size
100u
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Lactate dehydrogenase (LDH) is present in a wide variety of organisms, including plants and animals. It is an oxidoreductase which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called Hydroxybutyrate Dehydrogenase (HBD). There are 5 different isoenzymes of LDH, LDH1 to LDH5, each composed of 4 subunits which may be of 2 different types-M and H subunits. These subunits are encoded by two different genes: The M subunit is encoded by gene LDHA whilst the H subunit is encoded by LDHB. Usually LDH2 is the predominant form in the serum. An LDH1 level higher than the LDH2 level suggests myocardial infarction (damage to heart tissues releases heart LDH, which is rich in LDH1, into the bloodstream). Activity: ~1000 Units/ml @ 37ºC Dimension Protein: ~3mg Protein/ml (Commassie) Specific Activity: ~200 Units/mg Protein Unit Definition: One unit will catalyze the oxidation of one micromole of L-lactate to pyruvate per minute at 37°C and pH 8.55. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | Human liver |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight |
Product Properties
| Storage | 4°C Do Not Freeze |
| Grade | Purified |
| Purity | Purified by Immunoelectrophoresis. Contaminants: ALP: < 0.03%; CK: 1.5%; GOT: < 0.1%; GGT: < 0.02%; GPT: < 0.04% |
| Form | Supplied as a liquid in 3.1M ammonium sulfate, 50mM Tris-chloride, 1mM DTT, 1mM EDTA, pH 8.3. |
| Reactivity Life | 12 months |
| Note | For reserch purpose only |
Target Gene
NA
