Pepsinogen II, Human (Pepsinogen C)
537.08 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-171719
Supplier
US Biologicals
Size
100 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Pepsinogen II or pepsinogen C belongs to a group of aspartic proteinase zymogens (inactive form) that are activated in the acid pH of stomach to active enzyme pepsin. Pepsinogen II (PG II) is produced by chief cells and mucus neck cells of gastric mucosa, pyloric glands in the antrum and Brunner’s glands in the proximal duodenum. Serum concentration of PG II reflects the histological status of gastric mucosa. The ratio of concentration of PGI to PGII in serum of normal subjects is about 4:1. The PGI/PGII ratio decreases linearly with increasing grade of atrophic gastritis in the corpus. The ratio is 1000Units/mg (After Activation) One unit will produce an OD280nm of 0.001/minute at pH 2.0 and 37°C, measured as TCA-soluble products using hemoglobin as substrate. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | Human Gastric Mucosa |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight |
Product Properties
| Storage | -20°C |
| Grade | Highly Purified |
| Purity | ~90% (SDS-PAGE) |
| Form | Supplied as a lyophilized powder in Tris Chloride, pH 8.5. Reconstitute to ~1mg/ml in saline, pH 8.0. |
| Reactivity Life | 12 months |
| Note | For reserch purpose only |
Target Gene
NA
