Platelet Factor-4, Human (CXCL4)
466.67 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-209145
Supplier
US Biologicals
Size
5 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Platelet factor-4 is a 70aa protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemokine family. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy. Source: Platelet factor-4, from human platelets Molecular Weight: ~7.8kD Activity Control: Binding of HIT-antibodies Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | Human platelets |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 7.8 |
Product Properties
| Storage | -20°C |
| Grade | Highly Purified |
| Purity | ~95% (RP-HPLC, SDS-PAGE) |
| Form | Supplied as a lyophilized powder. No preservative added. Reconstitute in 100ul sterile ddH2O for 1mg/ml stock |
| Reactivity Life | 12 months |
| Note | For reserch purpose only |
Target Gene
NA
