PRDX3, Recombinant, Human (Thioredoxin-dependent Peroxide Reductase, Mitochondrial, Peroxiredoxin-3, Peroxiredoxin III, PRX III, Antioxidant Protein 1, AOP-1, Protein MER5 Homolog, HBC189, AOP1)
504.30 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-P3352-20J
Supplier
US Biologicals
Size
250 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the aa sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30kD in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol (1). Source: Recombinant corresponding to aa63-256, without mitochondrial leader sequence, from human Peroxiredoxin 3, expressed in E.coli. Molecular Weight: ~21.6kD Specific Activity: 1.2U/mg (One unit will cause the oxidation of 1umole of NADPH at 25°C at pH 7.5) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Source Antigen | Recombinant, E.coli |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 21.6 |
Product Properties
| Storage | -70°C |
| Grade | Highly Purified |
| Purity | ~95% (SDS-PAGE) |
| Form | Supplied as a liquid in 20mM HEPES, pH 7.0, 10% glycerol. |
| Reactivity Life | 6 months |
| Note | For reserch purpose only |
Target Gene
NA
