Pro-SAAS, aa245-254, Rat
464.49 $
For reserch purpose only
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
USB-302127
Supplier
US Biologicals
Size
200 µg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | ProSAAS is a newly discovered protein with a neuroendocrine distribution generally similar to that of prohormone convertase 1 (PC1), a peptide processing endopeptidase. ProSAAS mRNA is broadly distributed among neurons in brain and other neuroendocrine tissues (pituitary, adrenal, pancreas). Overexpression of ProSAAS in the AtT-20 cells substantially reduces the rate of processing of POMC(endogenous prohormone proopiomelanocortin) [1]. In wild type mouse brain and pituitary, the majority of ProSAAS is processed into smaller peptides including Little SAAS, PEN and big LEN.[2] A few obesity related propeptides have been processed by PC1 and obesity has been observed to be associated with mutations in the human PC1 gene[3].Does proSAAS- derived peptides play a role in the development of obesity? Source: aa245-254, Rat Molecular Weight: ~1013.07 Sequence: Leu-Glu-Asn-Ser-Ser-Pro-Gln-Ala-Pro-Ala Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Source Antigen | |
| Reactivity | |
| Cross Reactivity | |
| Applications | |
| Molecular Weight | 1013.07 |
Product Properties
| Storage | 4°C |
| Grade | Highly Purified |
| Purity | ~95% (HPLC) |
| Form | Supplied as a white powder. |
| Reactivity Life | 12 months |
| Note | For reserch purpose only |
Target Gene
NA
